Python CLI for HCMV antiviral resistance mutation detection and gB genotyping via NGS amplicon sequencing
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hcmv-resist

Python CLI for HCMV antiviral resistance mutation detection and gB genotyping via NGS amplicon sequencing.

Implements the pipeline from:

Arnedo-Muñoz et al. (2025). A New Next-Generation Sequencing Approach in Human Cytomegalovirus for the Identification of Antiviral Resistance Mutations and Genotypic Classification. J Med Virol. 97:e70523. PMID: 40736009

Architecture

This project follows Git Flow:

Branch Purpose
main Stable releases only
develop Active development, feature integration
feature/* Individual features (branched from develop)
release/* Release preparation (branched from develop)
hotfix/* Critical fixes to main

All code, CI, tests, and documentation live on develop.

Quick Start

See the develop branch for:

  • Full documentation and README
  • Source code and CLI reference
  • Installation instructions (conda/pip)
  • CI/CD configuration
  • Test suite

Installation

# Via conda (Forgejo)
micromamba install -c https://git.reslate.solutions/api/packages/ross/conda hcmv-resist

# Via pip (Forgejo)
pip install hcmv-resist --index-url https://git.reslate.solutions/api/packages/ross/pypi/simple

License

MIT License — see LICENSE